John J. DeStefano, MD

Subspecialty: Cataract, Primary Eye Care

Areas of Interest

  • Cataract surgery
  • Laser surgery
  • Complex corneal diseases


John DeStafeno, MD is a board-certified ophthalmologist specializing in all aspects of refractive cataract surgery and laser surgery as well as the treatment of complex corneal diseases. He completed his 2-year fellowship at Duke University which focused on clinical research and the medical and surgical management of anterior segment disease.

He is one of the most experienced cataract and refractive surgeons in the region, and has received recognition both locally and nationally for his excellence in eye care. His accolades include numerous Top Doctor and Surgeon awards, as well as the prestigious American Academy of Ophthalmology Achievement Award for his dedication to enhancing the field. In addition, he also enjoys educating the future of eye care, as he instructs ophthalmology residents at Wills Eye Hospital in Philadelphia.

Dr. DeStafeno was led to a career in medicine by the unique opportunity to impact a person’s life in a positive way. He will treat you with compassion while listening to your needs and desires to ensure the best surgical and medical care for your eyes and vision. There are few things in life more vital than vision, and he understands and values the trust you place in him.

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Board Certification
American Board of Ophthalmology


  • Fellowship:  Duke University Eye Center, cornea, refractive and external disease
  • Residency:  Albert Einstein College of Medicine, Long Island Jewish Hospital, Albert Einstein College of Medicine
  • Medical School:  Albany Medical College
  • Undergraduate:  Siena College, summa cum laude

Honors and Awards

  • American Academy of Ophthalmology Achievement Award
  • Top 300 Refractive Cataract Surgeons, Ocular Surgery News
  • “Top Doctor” Main Line Today magazine
  • “Top Doctors” Philadelphia magazine 2023-2024
  • Top 250 Premium IOL Surgeons,  Premier Surgeon magazine
  • Alpha Omega Alpha Medical Honor Society

Language Spoken


Wills Eye Hospital
840 Walnut Street, Suite 1230
Philadelphia, PA 19107 Google Maps