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Medical research leading to medical progress involves participation of human volunteers,. Your involvement is important: it helps us to uncover better ways to treat, prevent, diagnose and understand human disease.
Wills Eye Hospital invites patients and the community to participate in innovative clinical trials and research studies.
Click on a link below for studies that are recruiting now.
Participation in all clinical trials is voluntary and patients may choose to withdraw from any study at any time. Most of our clinical trials are sponsored by the federally-funded National Institutes of Health (NIH) or pharmaceutical and biotechnology companies. ClinicalTrials.Gov lists these and other clinical trials.
At Wills Eye, excellence in patient care is our top priority. Part of this commitment involves conducting medical research with the goal of helping our patients live longer, healthier lives with the best vision possible. Randomized clinical trials are the gold standard for conducting clinical research. These studies determine the treatments that are safe and beneficial to patients and guide patient management. This research is a joint effort between researchers, clinicians and patients. Successful studies depend on individuals’ willingness to participate as human volunteers (also called participants) to allow the advancement of medical knowledge.
Researchers at Wills Eye implement and conduct clinical trials in accordance with the highest standards. Clinical trials (Phase 3) evaluate whether a new treatment works better than an existing treatment. Other clinical trial types (Phase 1 and 2)will tell us more about the side effects, or what happens to the drug in the body. In other types of studies, researchers also want to look at the course of a disease and/or the impact a treatment has on you and your life. Below are the different types of clinical studies we conduct.
In an observational study, investigators assess health outcomes in groups of participants according to a research plan or protocol. Observational studies can help to understand risk factors for disease, factors that influence change in the course of disease over time and how disease impacts quality of life. These studies can be a retrospective (collect information from the past) or prospective design (following patients over time). Participants may receive interventions (which can include medical products such as drugs or devices) or procedures as part of their routine medical care, but participants are not assigned to specific interventions by the investigator (as in a clinical trial).
In a clinical trial, participants are randomized to receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or changes to participants' behavior, such as diet. Clinical trials may compare a new medical approach to a standard one that is already available, to a placebo that contains no active ingredients, or to no intervention. Results from clinical trials are used to guide treatment decisions.