The cornea can develop an infection. Such infections can be mild to severe. Risk factors for infection include contact lens wear, eye trauma and certain corneal conditions. Mild infections are often treated with frequent antibiotic drops. More severe infections may be cultured in the office or emergency room and then treated with frequent specially-made fortified antibiotics around the clock. Patients with severe corneal ulcers are seen regularly, often every day, until the infection appears to be improving. Most corneal ulcers resolve with antibiotic drop treatment.