Hyman Header
Leslie Hyman

Vice Chair for Research
Vickie and Jack Farber Vision Research Center at Wills Eye
Wills Eye Hospital
Thomas D. Duane Endowed Chair
Professor and Vice Chair of Research, Ophthalmology
Sidney Kimmel Medical College at Thomas Jefferson University

Dr. Hyman is an ocular epidemiologist with expertise in observational epidemiologic studies and clinical trials.  She earned her Ph.D. in Epidemiology from The Johns Hopkins University School of Hygiene and Public Health (now Bloomberg School of Public Health). She was recruited to the Department of Preventive Medicine at Stony Brook University Medical Center, Stony Brook, New York, where in 2004 she was named to Head of the Division of Epidemiology and Biostatistics.

In September 2016, she joined Wills Eye as Vice Chair for Research and was named the Thomas D. Duane Endowed Chair, Professor and Vice Chair of Research in the Department of Ophthalmology at the Sidney Kimmel Medical College of Thomas Jefferson University and Co-Director of the Wills Vision Research Center at Jefferson.

Dr. Hyman has served on a number of  professional and scientific committees and boards including the Editorial Board for Archives of Ophthalmology (JAMA Ophthalmology), NIH/National Eye Institute Strategic Planning Committees, NIH Study Sections, the Scientific Advisory Board of Foundation Fighting Blindness, and various NIH funded Study Advisory and Data and Safety Monitoring Committees. She has had leadership positions in the Association for Research in Vision and Ophthalmology (ARVO), and The American Academy of Ophthalmology (AAO). She is a fellow of ARVO, the American College of Epidemiology and the American Academy of Optometry.

Dr. Hyman's research has focused on identifying causes, risk factors and treatment of the leading causes of visual impairment and blindness. Her work on macular degeneration helped lay the foundation for future research on its causes and treatments.  She has also done extensive work in myopia progression and stabilization in children, evaluating treatment for glaucoma, and examining how hypertension and cardiovascular risk factors impact causes of visual decline.  Her work outside the field of vision research includes the study of the role of periodontal therapy on diabetes management. Dr. Hyman played crucial roles in seminal vision research studies including the Correction of Myopia Evaluation Trial (COMET) Eye Study, the Early Manifest Glaucoma Trial (EMGT) and the Barbados Eye Study.

Baş Z, Sharpe J, Yaghy A, Zhang Q, Shields CL, Hyman L; IRIS Registry Analytic Center Consortium. Prevalence of and Associated Factors for Eyelid Cancer in the American Academy of Ophthalmology Intelligent Research in Sight Registry. Ophthalmol Sci. 2022 Sep 27;3(1):100227. doi: 10.1016/j.xops.2022.100227. PMID: 36439695; PMCID: PMC9692036.

Lee CS, Blazes M, Lorch A, Pershing S, Hyman L, Ho AC, Haller J, Miller JW, Chew EY, Lum F, Lee AY. American Academy of Ophthalmology Intelligent Research in Sight (IRIS®) Registry and the IRIS Registry Analytic Center Consortium. Ophthalmol Sci. 2022 Jan 8;2(1):100112. doi: 10.1016/j.xops.2022.100112. PMID: 36246182; PMCID: PMC9560568.

Rezapour J, Bowd C, Dohleman J, Belghith A, Proudfoot JA, Christopher M, Hyman L, Jonas JB, Penteado RC, Moghimi S, Hou H, El-Nimri NW, Micheletti E, Fazio MA, Weinreb RN, Zangwill LM. Macula structural and vascular differences in glaucoma eyes with and without high axial myopia. Br J Ophthalmol. 2022 Jun 20:bjophthalmol-2021-320430. doi: 10.1136/bjophthalmol-2021-320430. Epub ahead of print. PMID: 35725293.

Bowd C, Belghith A, Rezapour J, Christopher M, Hyman L, Jonas JB, Weinreb RN, Zangwill LM. Diagnostic Accuracy of Macular Thickness Map and Texture En Face Images for Detecting Glaucoma in Eyes With Axial High Myopia. Am J Ophthalmol. 2022 Oct;242:26-35. doi: 10.1016/j.ajo.2022.04.019. Epub 2022 May 2. PMID: 35513028.

Rezapour J, Proudfoot JA, Bowd C, Dohleman J, Christopher M, Belghith A, Vega SM, Dirkes K, Suh MH, Jonas JB, Hyman L, Fazio MA, Sella R, Afshari NA, Weinreb RN, Zangwill LM. Bruch Membrane Opening Detection Accuracy in Healthy Eyes and Eyes With Glaucoma With and Without Axial High Myopia in an American and Korean Cohort. Am J Ophthalmol. 2022 May;237:221-234. doi: 10.1016/j.ajo.2021.11.030. Epub 2021 Dec 10. PMID: 34902327; PMCID: PMC9754118.

Lacy M, Kung TH, Owen JP, Yanagihara RT, Blazes M, Pershing S, Hyman LG, Van Gelder RN, Lee AY, Lee CS; IRIS® Registry Analytic Center Consortium. Endophthalmitis Rate in Immediately Sequential versus Delayed Sequential Bilateral Cataract Surgery within the Intelligent Research in Sight (IRIS®) Registry Data. Ophthalmology. 2022 Feb;129(2):129-138. doi: 10.1016/j.ophtha.2021.07.008. Epub 2021 Jul 13. PMID: 34265315; PMCID: PMC8755857.

Garrigan H, Hamati J, Lalakia P, Frasso R, Salzman B, Hyman L. Does Age-Related Macular Degeneration (AMD) Treatment Influence Patient Falls and Mobility? A Systematic Review. Ophthalmic Epidemiol. 2022 Apr;29(2):128-138. doi: 10.1080/09286586.2021.1921227. Epub 2021 May 17. PMID: 33993827.

Li Y, Hall NE, Pershing S, Hyman L, Haller JA, Lee AY, Lee CS, Chiang M, Lum F, Miller JW, Lorch A, Elze T. Age, Gender, and Laterality of Retinal Vascular Occlusion: A Retrospective Study from the IRIS® Registry. Ophthalmol Retina. 2022 Feb;6(2):161-171. doi: 10.1016/j.oret.2021.05.004. Epub 2021 May 12. PMID: 33991710; PMCID: PMC9178780.

Rezapour J, Bowd C, Dohleman J, Belghith A, Proudfoot JA, Christopher M, Hyman L, Jonas JB, Fazio MA, Weinreb RN, Zangwill LM. The influence of axial myopia on optic disc characteristics of glaucoma eyes. Sci Rep. 2021 Apr 23;11(1):8854. doi: 10.1038/s41598-021-88406-1. PMID: 33893383; PMCID: PMC8065167.

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