Salzmann’s Nodular Degeneration

For an unknown reason, some eyes develop one or more creamy white nodular elevations called Salzmann’s nodular degeneration. It is often mild and located at the edge of the cornea, not causing any symptoms, and can simply be followed. However, if the nodules are larger or more central, they may cause irritation and/or decreased vision. Lubrication, glasses, or contact lenses may be helpful. Occasionally surgical excision is warranted. Salzmann’s nodules can be removed with a blade or with an excimer laser (phototherapeutic keratectomy-PTK) with good success. The nodules sometimes recur after excision.